A robust in vivo model for B cell precursor acute lymphoblastic leukemia
نویسندگان
چکیده
منابع مشابه
A robust in vivo model for B cell precursor acute lymphoblastic leukemia.
B cell precursor acute lymphoblastic leukemia (BCP ALL) is the most common malignancy in children. While treatments have improved remarkably over the past four decades, resistant disease and late effects that result from cytotoxic chemotherapy remain serious problems for individuals with BCP ALL. Improved genetic tools have led to the discovery of numerous somatic mutations associated with BCP ...
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 2015
ISSN: 0021-9738
DOI: 10.1172/jci83799